Born in Japan, Natsuko began playing the violin at the age of three. She studied at the Yehudi Menuhin School and Royal Northern College of Music in England and the Curtis Institute of Music in Philadelphia. She received direct guidance and teaching under Lord Menuhin and Wen Zhou Li.

In great demand as a soloist, she has appeared with many world renowned orchestras including the London Symphony Orchestra, Philharmonia (London), Halle Orchestra, Odense Symphony (Denmark), Tokyo Symphony Orchestra, Tokyo Philharmonic, Orchestra Ensemble Kanazawa, Hong Kong Sinfonietta, Melbourne Symphony and Adelaide Symphony Orchestra.

Until 2020 Natsuko held the position of Concertmaster with the Adelaide Symphony Orchestra, and has recently accepted an engagement as Co-Concertmaster of the Queensland Symphony Orchestra. She frequently appears as guest Concertmaster with other major orchestras in Australia and Asia. She was the leader of the Australian String Quartet and then the Grainger Quartet until the end of 2008. She has performed and collaborated in chamber music with many illustrious musicians including Pinchas Zukerman, Heinz Holliger, Anthony Marwood, Cristina Ortiz, Jonathan Kelly, Li-Wei Qin and Brett Dean and continues to perform chamber music regularly as a guest artist with various groups and musicians.

Natsuko currently plays on a Giovanni Battista Guadagnini generously on loan from the South Australia Guadagnini Violin Trust and Ukaria.